O- desmethyltramadol ( also known as o- dsmt and desmetramadol) is an opioid substance of the cyclohexanol class. it is an active metabolite of tramadol. o- dsmt has no documented history of human use before it appeared for sale on the research chemical market in the s. desmetramadol ( inn), also known as o- desmethyltramadol ( o- dsmt), is an opioid analgesic and the main active metabolite of tramadol. tramadol is demethylated by the liver enzyme cyp2d6 in the same way as o desmethyltramadol in kratom codeine, and so similarly to the variation in effects seen with codeine, individuals who have a less active form of cyp2d6 ( " poor metabolizers" ) will tend to get reduced analgesic effects from. using lc– ms/ ms, we could detect “ kratom” alkaloids and o- desmethyltramadol, but not tramadol and n- desmethyltramadol. cannabis oil pain relief. these findings could confirm that “ krypton” is not only a herbal mixture with “ kratom” leaves, but contains also o- desmethyltramadol as a synthetic additive. materials and methods 2.
ndt t, claussen u, gussregen b, et al. kratom alkaloids and o- desmethyltramadol in urine of a " krypton" herbal mixture consumer. forensic sci int ; : 47- 52. the only thing we know for sure is that kratom killed nine young men in sweden back in after taking krypton kratom. not just any kratom product but krypton kratom, a specially- formulated kratom product that contained the kratom alkaloid mitragynine as well as a powerful mu- receptor agonist known as o- desmethyltramadol. both kratom and an additional preparation called krypton are available via the internet. it seems to consist of powdered kratom leaves with another mu- receptor agonist, o- desmethyltramadol, added. o- desmethyltramadol is an active metabolite of tramadol, a commonly prescribed analgesic. kronstrad, et al. unintentional fatal intoxications with mitragynine and o- desmethyltramadol from the herbal blend krypton. micrograms bulletin. i read that o- dsmt is also potentially caustic ( but also more active orally than u4 is).
is this true of recent batches? i was still planning on snorting to save product. also, how do the effects compare to both u- 4 and kratom? i was hoping for something pretty much in between in terms of effects ( and longer lived than u4). o- desmethyltramadol and kratom i realize this isnt the kratom subreddit, but i think this is probably the best place to ask this since most people havent heard of o- desmethyltramadol. ive had quite a bit of kratom for a while. lc- ms/ ms detected the " kratom" alkaloids mitragynine, speciociliatine, speciogynine, mitraciliatine, and paynantheine and approximately 9mg/ l o- desmethyltramadol, but no tramadol and n- desmethyltramadol. discussion: the detection of m. speciosa alkaloids is a proof of " kratom" abuse.